Heather M. Stapleton
Dan and Bunny Gabel Associate Professor of Environmental Ethics and Sustainable Environmental ManagementDr. Stapleton's research focuses on understanding the fate and transformation of organic contaminants in aquatic systems and in indoor environments. Her main focus has been on the bioaccumulation and biotransformation of brominated flame retardants, and specifically polybrominated diphenyl ethers,(PBDEs). Her current research projects explore the routes of human exposure to flame retardant chemicals and examine the way these compounds are photodegraded and metabolized using mass spectrometry to identify breakdown products/metabolites. She uses both in vivo techniques iwth fish, and in vitro techniques with cell cultures to examine metabolism of this varied class of chemicals. Also of interest to Dr. Stapleton is the study of the fate of PBDEs in the environment which may lead to bioaccumulation in aquatic systems and examining their bioavailability under different environmental conditions.
Appointments and Affiliations
- Dan and Bunny Gabel Associate Professor of Environmental Ethics and Sustainable Environmental Management
- Associate Professor of Environmental Sciences and Policy in the Nicholas School of the Environment
- Associate Professor in the Department of Civil and Environmental Engineering
- Member of the Duke Cancer Institute
- Office Location: 450 Research Drive, LSRC Room A220, Durham, NC 27519
- Office Phone: (919) 613-8717
- Email Address: firstname.lastname@example.org
- Ph.D. University of Maryland, College Park, 2003
- M.S. University of Maryland, College Park, 2000
- B.S. Long Island University Southhampton College, 1997
- CEE 563: Chemical Fate of Organic Compounds
- ENVIRON 360: Environmental Chemistry and Toxicology
- ENVIRON 393: Research Independent Study
- ENVIRON 394: Research Independent Study
- ENVIRON 540: Chemical Fate of Organic Compounds
- ENVIRON 593: Independent Studies and Projects
- ENVIRON 780: Environmental Exposure Analysis
- ENVIRON 898: Program Area Seminar
- ENVIRON 899: Master's Project
In the News
- Camping tents toxic? Duke study reveals troubling chemical exposure (May 18, 2016 | Gear Junkie )
- Four Pratt Faculty Listed Among Most Highly Cited (Jan 26, 2016)
- Heather Stapleton’s lab: Popular car seats found to contain flame retardant (Dec 21, 2015 | “CBS This Morning” )
- Are Flame Retardant Chemicals Fueling Thyroid Cancer? (Dec 14, 2015)
- Study finds toxic nail-polish chemicals in women's bodies (Oct 20, 2015 | Fox News )
- House dust chemicals activate receptor linked to obesity (Jul 30, 2015 | Chemical Watch )
- House Dust May Trigger Obesity Receptor (Jul 28, 2015)
- Why more scientists are speaking out on contentious issues (Jun 12, 2015 | National Geographic )
- How to test a couch for toxins (Sep 29, 2014 | The Atlantic )
- Moms and toddlers may be at risk -- from sofas (Sep 22, 2014 | The News & Observer )
- Macaulay, LJ; Chernick, M; Chen, A; Hinton, DE; Bailey, JM; Kullman, SW; Levin, ED; Stapleton, HM, Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development., Environmental Toxicology & Chemistry, vol 36 no. 1 (2017), pp. 36-48 [10.1002/etc.3535] [abs].
- Leonetti, C; Butt, CM; Hoffman, K; Hammel, SC; Miranda, ML; Stapleton, HM, Brominated flame retardants in placental tissues: associations with infant sex and thyroid hormone endpoints., Environmental Health, vol 15 no. 1 (2016) [10.1186/s12940-016-0199-8] [abs].
- Phillips, AL; Chen, A; Rock, KD; Horman, B; Patisaul, HB; Stapleton, HM, Editor's Highlight: Transplacental and Lactational Transfer of Firemaster® 550 Components in Dosed Wistar Rats., Toxicological Sciences (Elsevier), vol 153 no. 2 (2016), pp. 246-257 [10.1093/toxsci/kfw122] [abs].
- Cooper, EM; Kroeger, G; Davis, K; Clark, CR; Ferguson, PL; Stapleton, HM, Results from Screening Polyurethane Foam Based Consumer Products for Flame Retardant Chemicals: Assessing Impacts on the Change in the Furniture Flammability Standards., Environmental Science & Technology, vol 50 no. 19 (2016), pp. 10653-10660 [10.1021/acs.est.6b01602] [abs].
- Butt, CM; Hoffman, K; Chen, A; Lorenzo, A; Congleton, J; Stapleton, HM, Regional comparison of organophosphate flame retardant (PFR) urinary metabolites and tetrabromobenzoic acid (TBBA) in mother-toddler pairs from California and New Jersey., Environment International, vol 94 (2016), pp. 627-634 [10.1016/j.envint.2016.06.029] [abs].