Heather M. Stapleton

Research Interests

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• Human exposure in indoor environments
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• Use of silicone wristbands to measure human exposure
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• Chemical exposures and cancer risk
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• Targeted & Nontargeted mass spectrometry methods applied to environmental samples
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• Effects of halogenated organic contaminants (e.g. BFRs, PFAS) on thyroid hormone regulation
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Bio

Professor Heather Stapleton is an environmental chemist and exposure scientist in the Nicholas School of the Environment at Duke University.  Her research interests focus on identification of halogenated and organophosphate chemicals in building materials, furnishings and consumer products, and estimation of human exposure, particularly in vulnerable populations such as pregnant women and children.  Her laboratory utilizes mass spectrometry, including targeted and nontargeted approaches, to characterize chemical burdens in both environmental samples and biological tissues to support environmental health research. Currently she serves as the Director for the Duke Superfund Research Center, and Director of the Duke Environmental Analysis Laboratory, which is part of NIH’s Human Health Environmental Analysis Resource.

 

Education

• B.S. Long Island University, Southhampton College, 1997
• M.S. University of Maryland, College Park, 2000
• Ph.D. University of Maryland, College Park, 2003

Positions

• Ronie-Richele Garcia-Johnson Distinguished Professor
• Professor
• Professor in the Department of Civil and Environmental Engineering
• Member of the Duke Cancer Institute

Awards, Honors, and Distinctions

• Highly Cited Researcher in the field of Environment. Clarivate. 2021
• Thomas Langford Lectureship Award. Duke University. 2020
• Highly Cited Researcher. Clarivate. 2019
• Best Paper of the Year Award. Environmental Science & Technology. 2011

Courses Taught

• ENVIRON 899: Master's Project
• ENVIRON 898: Program Area Seminar
• ENVIRON 540: Chemical Fate of Organic Compounds
• ENVIRON 393: Research Independent Study
• ENVIRON 360: Environmental Health: Pollutant Chemistry and Toxicology
• CEE 563: Chemical Fate of Organic Compounds

Publications

• Wise CF, Herkert NJ, Hoffman K, Vaden S, Breen M, Stapleton HM. Environmental Exposures and Canine Bladder Cancer: A Case Control Study Using Silicone Passive Samplers. Environmental science & technology. 2025 Jan;
• Baker BH, Day DB, Hazlehurst MF, Herkert NJ, Stapleton HM, Sathyanarayana S. Associations of environmental chemical exposures measured in personal silicone wristbands with sociodemographic factors, COVID-19 restrictions, and child respiratory health. Environmental research. 2024 Dec;262(Pt 1):119776.
• Fowler CH, Reuben A, Stapleton HM, Hoffman K, Herkert N, Barakat L, et al. Children's exposure to chemical contaminants: Demographic disparities and associations with the developing basal ganglia. Environmental research. 2024 Dec;263(Pt 1):119990.
• Gaballah S, Hormon B, Armour Mason Nelson GS, Cao J, Hoffman K, Patisaul HB, et al. Distribution of Polybrominated Diphenyl Ethers (PBDEs) in Placental Tissues of Maternal and Fetal Origin in Exposed Wistar Rats and Associations with Thyroid Hormone Levels. Toxicological sciences : an official journal of the Society of Toxicology. 2024 Nov;kfae151.
• Reddam A, Herkert N, Stapleton HM, Volz DC. Silicone wristbands reveal ubiquitous human exposure to ortho-phthalates and non-ortho-phthalate plasticizers in Southern California. Environmental research. 2024 Oct;258:119465.
• Hickman E, Frey J, Wylie A, Hartwell HJ, Herkert NJ, Short SJ, et al. Chemical and non-chemical stressors in a postpartum cohort through wristband and self report data: Links between increased chemical burden, economic, and racial stress. Environment international. 2024 Sep;191:108976.
• Hoxie T, Zhang S, Herkert NJ, Bauer RA, Guo Y, Bhattacharya A, et al. Silicone Wristbands as a Personal Passive Sampler to Evaluate Indoor Exposure to Volatile and Non-volatile PFASs. Environmental science & technology. 2024 Sep;58(37):16316–26.
• Herkert NJ, Getzinger GJ, Hoffman K, Young AS, Allen JG, Levasseur JL, et al. Wristband Personal Passive Samplers and Suspect Screening Methods Highlight Gender Disparities in Chemical Exposures. Environmental science & technology. 2024 Sep;58(35):15497–510.
• Wise CF, Breen M, Stapleton HM. Canine on the Couch: The New Canary in the Coal Mine for Environmental Health Research. Environment & health (Washington, DC). 2024 Aug;2(8):517–29.
• Hoffman K, Tang X, Cooper EM, Hammel SC, Sjodin A, Phillips AL, et al. Children's exposure to brominated flame retardants in the home: The TESIE study. Environmental pollution (Barking, Essex : 1987). 2024 Jul;352:124110.
• Levasseur JL, Hoffman K, Zhang S, Cooper EM, Stapleton HM. Monitoring human exposure to four parabens and triclosan: comparing silicone wristbands with spot urine samples as predictors of internal dose. Journal of exposure science & environmental epidemiology. 2024 Jul;34(4):670–8.
• Leuthner TC, Zhang S, Kohrn BF, Stapleton HM, Baugh LR. Structure-specific variation in per- and polyfluoroalkyl substances toxicity among genetically diverse Caenorhabditis elegans strains. bioRxiv. 2024 Jun 2;
• Samon SM, Hoffman K, Herkert N, Stapleton HM. Chemical uptake into silicone wristbands over a five day period. Environmental pollution (Barking, Essex : 1987). 2024 May;349:123877.
• Hoehn RM, Jahl LG, Herkert NJ, Hoffman K, Soehl A, Diamond ML, et al. Flame Retardant Exposure in Vehicles Is Influenced by Use in Seat Foam and Temperature. Environmental science & technology. 2024 May;58(20):8825–34.
• Blum A, Behl M, Birnbaum LS, Diamond ML, Phillips A, Singla V, et al. Correction to “Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers?”. Environmental Science & Technology Letters. 2024 Mar 12;11(3):287–287.
• Lin Y, Wang X, Chen R, Weil T, Ge Y, Stapleton HM, et al. Arachidonic Acid Metabolites in Self-collected Biospecimens Following Campfire Exposure: Exploring Non-invasive Biomarkers of Wildfire Health Effects. Environmental science & technology letters. 2024 Mar;11(3):201–7.
• Matheson R, Sexton CL, Wise CF, O’Brien J, Keyser AJ, Kauffman M, et al. Silicone tags as an effective method of monitoring environmental contaminant exposures in a geographically diverse sample of dogs from the Dog Aging Project. Frontiers in veterinary science. 2024 Jan;11:1394061.
• Chen X, Birnbaum LS, Babich MA, de Boer J, White KW, Barone S, et al. Opportunities in Assessing and Regulating Organohalogen Flame Retardants (OFRs) as a Class in Consumer Products. Environmental health perspectives. 2024 Jan;132(1):15001.
• Overdahl KE, Tighe RM, Stapleton HM, Ferguson PL. Investigating sensitization activity of azobenzene disperse dyes via the Direct Peptide Reactivity Assay (DPRA). Food Chem Toxicol. 2023 Dec;182:114108.
• Overdahl KE, Kassotis CD, Hoffman K, Getzinger GJ, Phillips A, Hammel S, et al. Characterizing azobenzene disperse dyes and related compounds in house dust and their correlations with other organic contaminant classes. Environmental pollution (Barking, Essex : 1987). 2023 Nov;337:122491.
• Wiegand J, Hoang J, Avila-Barnard S, Nemarugommula C, Ha M, Zhang S, et al. Triphenyl phosphate-induced pericardial edema in zebrafish embryos is reversible following depuration in clean water. Aquatic toxicology (Amsterdam, Netherlands). 2023 Oct;263:106699.
• Hall SM, Zhang S, Tait GH, Hoffman K, Collier DN, Hoppin JA, et al. PFAS levels in paired drinking water and serum samples collected from an exposed community in Central North Carolina. The Science of the total environment. 2023 Oct;895:165091.
• Samon S, Herkert N, Ghassabian A, Liu H, Hammel SC, Trasande L, et al. Measuring semi-volatile organic compound exposures during pregnancy using silicone wristbands. Chemosphere. 2023 Oct;339:139778.
• Carignan CC, Bauer RA, Patterson A, Phomsopha T, Redman E, Stapleton HM, et al. Self-Collection Blood Test for PFASs: Comparing Volumetric Microsamplers with a Traditional Serum Approach. Environmental science & technology. 2023 May;57(21):7950–7.
• Ruis M, Hoffman K, Stapleton HM. Brominated flame retardants and legacy organochlorines in archived human placenta samples: Sex differences, temporal analysis and associations with infant birth weight. Chemosphere. 2023 May;322:138170.
• Crute CE, Landon CD, Garner A, Hall SM, Everitt JI, Zhang S, et al. Maternal exposure to perfluorobutane sulfonate (PFBS) during pregnancy: evidence of adverse maternal and fetoplacental effects in New Zealand White (NZW) rabbits. Toxicol Sci. 2023 Feb 17;191(2):239–52.
• Young AS, Herkert N, Stapleton HM, Coull BA, Hauser R, Zoeller T, et al. Hormone receptor activities of complex mixtures of known and suspect chemicals in personal silicone wristband samplers worn in office buildings. Chemosphere. 2023 Feb;315:137705.
• Wiegand J, Avila-Barnard S, Nemarugommula C, Lyons D, Zhang S, Stapleton HM, et al. Triphenyl phosphate-induced pericardial edema in zebrafish embryos is dependent on the ionic strength of exposure media. Environment international. 2023 Feb;172:107757.
• Wiegand J, Avila-Barnard SG, Nemarugommula C, Lyons D, Zhang S, Stapleton HM, et al. Triphenyl Phosphate-Induced Pericardial Edema in Zebrafish Embryos is Dependent on the Ionic Strength of Exposure Media. In: BIRTH DEFECTS RESEARCH. 2023. p. 875–875.
• Samon SM, Hammel SC, Stapleton HM, Anderson KA. Silicone wristbands as personal passive sampling devices: Current knowledge, recommendations for use, and future directions. Environment international. 2022 Nov;169:107339.
• Crute CE, Hall SM, Landon CD, Garner A, Everitt JI, Zhang S, et al. Evaluating maternal exposure to an environmental per and polyfluoroalkyl substances (PFAS) mixture during pregnancy: Adverse maternal and fetoplacental effects in a New Zealand White (NZW) rabbit model. Sci Total Environ. 2022 Sep 10;838(Pt 4):156499.
• Hammel SC, Nordone S, Zhang S, Lorenzo AM, Eichner B, Moody MA, et al. Infants' diminished response to DTaP vaccine is associated with exposure to organophosphate esters. The Science of the total environment. 2022 Sep;837:155782.
• Habre R, Dorman DC, Abbatt J, Bahnfleth WP, Carter E, Farmer D, et al. Why Indoor Chemistry Matters: A National Academies Consensus Report. Environmental science & technology. 2022 Aug;56(15):10560–3.
• Levasseur JL, Hoffman K, Herkert NJ, Cooper E, Hay D, Stapleton HM. Characterizing firefighter's exposure to over 130 SVOCs using silicone wristbands: A pilot study comparing on-duty and off-duty exposures. The Science of the total environment. 2022 Aug;834:155237.
• Pétré M-A, Salk KR, Stapleton HM, Ferguson PL, Tait G, Obenour DR, et al. Per- and polyfluoroalkyl substances (PFAS) in river discharge: Modeling loads upstream and downstream of a PFAS manufacturing plant in the Cape Fear watershed, North Carolina. The Science of the total environment. 2022 Jul;831:154763.
• Hall SM, Zhang S, Hoffman K, Miranda ML, Stapleton HM. Concentrations of per- and polyfluoroalkyl substances (PFAS) in human placental tissues and associations with birth outcomes. Chemosphere. 2022 May;295:133873.
• Reddam A, Herkert N, Stapleton HM, Volz DC. Partial dust removal in vehicles does not mitigate human exposure to organophosphate esters. Environmental research. 2022 Apr;205:112525.
• Wang Z, Wade AM, Richter DD, Stapleton HM, Kaste JM, Vengosh A. Legacy of anthropogenic lead in urban soils: Co-occurrence with metal(loids) and fallout radionuclides, isotopic fingerprinting, and in vitro bioaccessibility. The Science of the total environment. 2022 Feb;806(Pt 3):151276.
• Herkert NJ, Kassotis CD, Zhang S, Han Y, Pulikkal VF, Sun M, et al. Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their In Vitro Adipogenic Activity. Environmental science & technology. 2022 Jan;56(2):1162–73.
• Wise CF, Hammel SC, Herkert NJ, Ospina M, Calafat AM, Breen M, et al. Comparative Assessment of Pesticide Exposures in Domestic Dogs and Their Owners Using Silicone Passive Samplers and Biomonitoring. Environmental science & technology. 2022 Jan;56(2):1149–61.
• Kozlova EV, Valdez MC, Denys ME, Bishay AE, Krum JM, Rabbani KM, et al. Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71. Archives of toxicology. 2022 Jan;96(1):335–65.
• Jenkins JA, Baudoin BA, Johnson D, Fernie KJ, Stapleton HM, Karouna-Renier NK. Establishment of baseline cytology metrics in nestling American kestrels (Falco sparverius): Immunomodulatory effects of the flame retardant isopropylated triarylphosphate isomers. Environment international. 2021 Dec;157:106779.
• Young AS, Herkert N, Stapleton HM, Cedeño Laurent JG, Jones ER, MacNaughton P, et al. Chemical contaminant exposures assessed using silicone wristbands among occupants in office buildings in the USA, UK, China, and India. Environment international. 2021 Nov;156:106727.
• Overdahl KE, Gooden D, Bobay B, Getzinger GJ, Stapleton HM, Ferguson PL. Characterizing azobenzene disperse dyes in commercial mixtures and children's polyester clothing. Environ Pollut. 2021 Oct 15;287:117299.
• Patisaul HB, Behl M, Birnbaum LS, Blum A, Diamond ML, Rojello Fernández S, et al. Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers. Environmental health perspectives. 2021 Oct;129(10):105001.
• Hoffman K, Levasseur JL, Zhang S, Hay D, Herkert NJ, Stapleton HM. Monitoring Human Exposure to Organophosphate Esters: Comparing Silicone Wristbands with Spot Urine Samples as Predictors of Internal Dose. Environmental science & technology letters. 2021 Sep;8(9):805–10.
• Kassotis CD, Hoffman K, Völker J, Pu Y, Veiga-Lopez A, Kim SM, et al. Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study. Toxicology. 2021 Sep;461:152900.
• Wang Z, Coyte RM, Cowan EA, Stapleton HM, Dwyer GS, Vengosh A. Evaluation and Integration of Geochemical Indicators for Detecting Trace Levels of Coal Fly Ash in Soils. Environmental science & technology. 2021 Aug;55(15):10387–97.
• Gillera SEA, Marinello WP, Cao KT, Horman BM, Stapleton HM, Patisaul HB. Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture. Endocrinology. 2021 Aug;162(8):bqab100.
• Kassotis CD, Hoffman K, Phillips AL, Zhang S, Cooper EM, Webster TF, et al. Characterization of adipogenic, PPARγ, and TRβ activities in house dust extracts and their associations with organic contaminants. The Science of the total environment. 2021 Mar;758:143707.
• Levasseur JL, Hammel SC, Hoffman K, Phillips AL, Zhang S, Ye X, et al. Young children's exposure to phenols in the home: Associations between house dust, hand wipes, silicone wristbands, and urinary biomarkers. Environment international. 2021 Feb;147:106317.
• Gardner CM, Hoffman K, Stapleton HM, Gunsch CK. Exposures to Semivolatile Organic Compounds in Indoor Environments and Associations with the Gut Microbiomes of Children. Environmental Science and Technology Letters. 2021 Jan 12;8(1):73–9.
• Hammel SC, Stapleton HM, Eichner B, Hoffman K. Reconsidering an Appropriate Urinary Biomarker for Flame Retardant Tris(1-chloro-2-propyl) Phosphate (TCIPP) Exposure in Children. Environmental Science and Technology Letters. 2021 Jan 12;8(1):80–5.
• Ingle ME, Mínguez-Alarcón L, Carignan CC, Stapleton HM, Williams PL, Ford JB, et al. Reproductive outcomes associated with flame retardants among couples seeking fertility treatment: A paternal perspective. Environmental research. 2021 Jan;192:110226.
• Kassotis CD, Herkert NJ, Hammel SC, Hoffman K, Xia Q, Kullman SW, et al. Thyroid Receptor Antagonism of Chemicals Extracted from Personal Silicone Wristbands within a Papillary Thyroid Cancer Pilot Study. Environmental science & technology. 2020 Dec;54(23):15296–312.
• Hall SM, Patton S, Petreas M, Zhang S, Phillips AL, Hoffman K, et al. Per- and Polyfluoroalkyl Substances in Dust Collected from Residential Homes and Fire Stations in North America. Environmental science & technology. 2020 Nov;54(22):14558–67.
• Witchey SK, Al Samara L, Horman BM, Stapleton HM, Patisaul HB. Perinatal exposure to FireMaster® 550 (FM550), brominated or organophosphate flame retardants produces sex and compound specific effects on adult Wistar rat socioemotional behavior. Hormones and behavior. 2020 Nov;126:104853.
• Hammel SC, Zhang S, Lorenzo AM, Eichner B, Stapleton HM, Hoffman K. Young infants' exposure to organophosphate esters: Breast milk as a potential source of exposure. Environ Int. 2020 Oct;143:106009.
• Kozlova EV, Chinthirla BD, Pérez PA, DiPatrizio NV, Argueta DA, Phillips AL, et al. Maternal transfer of environmentally relevant polybrominated diphenyl ethers (PBDEs) produces a diabetic phenotype and disrupts glucoregulatory hormones and hepatic endocannabinoids in adult mouse female offspring. Scientific reports. 2020 Oct;10(1):18102.
• Rock KD, St Armour G, Horman B, Phillips A, Ruis M, Stewart AK, et al. Effects of Prenatal Exposure to a Mixture of Organophosphate Flame Retardants on Placental Gene Expression and Serotonergic Innervation in the Fetal Rat Brain. Toxicological sciences : an official journal of the Society of Toxicology. 2020 Jul;176(1):203–23.
• Phillips AL, Herkert NJ, Ulrich JC, Hartman JH, Ruis MT, Cooper EM, et al. In Vitro Metabolism of Isopropylated and tert-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions. Chemical research in toxicology. 2020 Jun;33(6):1428–41.
• Wise CF, Hammel SC, Herkert N, Ma J, Motsinger-Reif A, Stapleton HM, et al. Comparative Exposure Assessment Using Silicone Passive Samplers Indicates That Domestic Dogs Are Sentinels To Support Human Health Research. Environmental science & technology. 2020 Jun;54(12):7409–19.
• Kuiper JR, Stapleton HM, Wills-Karp M, Wang X, Burd I, Buckley JP. Predictors and reproducibility of urinary organophosphate ester metabolite concentrations during pregnancy and associations with birth outcomes in an urban population. Environmental health : a global access science source. 2020 May;19(1):55.
• Ingle ME, Mínguez-Alarcón L, Carignan CC, Stapleton HM, Williams PL, Ford JB, et al. Exploring reproductive associations of serum polybrominated diphenyl ether and hydroxylated brominated diphenyl ether concentrations among women undergoing in vitro fertilization. Human reproduction (Oxford, England). 2020 May;35(5):1199–210.
• Gillera SEA, Marinello WP, Horman BM, Phillips AL, Ruis MT, Stapleton HM, et al. Sex-specific effects of perinatal FireMaster® 550 (FM 550) exposure on socioemotional behavior in prairie voles. Neurotoxicology and teratology. 2020 May;79:106840.
• Curras-Collazo M, Kozlova E, Stapleton H, Gonzalez G, Chinthirla BD, Krum JM. Sex‐Dependent Metabolic Syndrome Phenotype Produced By Developmental Exposure to Indoor Flame Retardants. In: The FASEB Journal. Wiley; 2020. p. 1–1.
• Hammel SC, Hoffman K, Phillips AL, Levasseur JL, Lorenzo AM, Webster TF, et al. Comparing the Use of Silicone Wristbands, Hand Wipes, And Dust to Evaluate Children's Exposure to Flame Retardants and Plasticizers. Environmental science & technology. 2020 Apr;54(7):4484–94.
• Herkert NJ, Merrill J, Peters C, Bollinger D, Zhang S, Hoffman K, et al. Assessing the effectiveness of point-of-use residential drinking water filters for perfluoroalkyl substances (pfass). Environmental Science and Technology Letters. 2020 Mar 10;7(3):178–84.
• Cooper EM, Rushing R, Hoffman K, Phillips AL, Hammel SC, Zylka MJ, et al. Strobilurin fungicides in house dust: is wallboard a source? Journal of exposure science & environmental epidemiology. 2020 Mar;30(2):247–52.
• Reddam A, Tait G, Herkert N, Hammel SC, Stapleton HM, Volz DC. Longer commutes are associated with increased human exposure to tris(1,3-dichloro-2-propyl) phosphate. Environment international. 2020 Mar;136:105499.
• Blake BE, Cope HA, Hall SM, Keys RD, Mahler BW, McCord J, et al. Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX). Environmental health perspectives. 2020 Feb;128(2):27006.
• Ingle ME, Mínguez-Alarcón L, Carignan CC, Butt CM, Stapleton HM, Williams PL, et al. The association of urinary phosphorous-containing flame retardant metabolites and self-reported personal care and household product use among couples seeking fertility treatment. Journal of exposure science & environmental epidemiology. 2020 Jan;30(1):107–16.
• Hoffman K, Stapleton HM. Papillary thyroid cancer clusters in North Carolina 1997-2017. In: CANCER PREVENTION RESEARCH. 2020. p. 36–36.
• Escher BI, Stapleton HM, Schymanski EL. Tracking complex mixtures of chemicals in our changing environment. Science (New York, NY). 2020 Jan;367(6476):388–92.
• Blake BE, Cope H, Hall S, Keys R, Mahler B, Mccord J, et al. Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Its Replacement GenX Induces Adverse Pregnancy Outcomes and Disrupts the Placenta. In: BIRTH DEFECTS RESEARCH. 2020. p. 823–823.
• Ruis MT, Stapleton HM. The Placenta: A Mediator of Thyroid Hormone Disruption Following Gestational Exposure to Flame Retardants. In: INTERNATIONAL JOURNAL OF TOXICOLOGY. SAGE PUBLICATIONS INC; 2020. p. 52–52.
• Craig JA, Ceballos DM, Fruh V, Petropoulos ZE, Allen JG, Calafat AM, et al. Exposure of Nail Salon Workers to Phthalates, Di(2-ethylhexyl) Terephthalate, and Organophosphate Esters: A Pilot Study. Environmental science & technology. 2019 Dec;53(24):14630–7.
• Doherty BT, Hammel SC, Daniels JL, Stapleton HM, Hoffman K. Organophosphate Esters: Are These Flame Retardants and Plasticizers Affecting Children's Health? Current environmental health reports. 2019 Dec;6(4):201–13.
• Bastiaensen M, Van den Eede N, Su G, Letcher RJ, Stapleton HM, Covaci A. Towards establishing indicative values for metabolites of organophosphate ester contaminants in human urine. Chemosphere. 2019 Dec;236:124348.
• Chanti-Ketterl M, Plassman B, Parks C, Herkert N, Fleenor J, Zhang S, et al. Validating Silicone Wristbands to Measure Pesticide Exposures Among Older Adults -- Proof-of-Concept Study. In 2019.
• Hammel SC, Levasseur JL, Hoffman K, Phillips AL, Lorenzo AM, Calafat AM, et al. Children's exposure to phthalates and non-phthalate plasticizers in the home: The TESIE study. Environment international. 2019 Nov;132:105061.
• Blum A, Behl M, Birnbaum L, Diamond ML, Phillips A, Singla V, et al. Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers? Environmental science & technology letters. 2019 Nov;6(11):638–49.
• Ruis MT, Rock KD, Hall SM, Horman B, Patisaul HB, Stapleton HM. PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation. Endocrinology. 2019 Nov;160(11):2748–58.
• Phillips AL, Stapleton HM. Inhibition of Human Liver Carboxylesterase (hCE1) by Organophosphate Ester Flame Retardants and Plasticizers: Implications for Pharmacotherapy. In: Toxicological sciences : an official journal of the Society of Toxicology. 2019. p. 396–405.
• de Boer J, Stapleton HM. Assess flame retardants with care-Response. Science (New York, NY). 2019 Sep;365(6457):993.
• Doherty BT, Hoffman K, Keil AP, Engel SM, Stapleton HM, Goldman BD, et al. Prenatal exposure to organophosphate esters and behavioral development in young children in the Pregnancy, Infection, and Nutrition Study. Neurotoxicology. 2019 Jul;73:150–60.
• Dembsey NA, Brokaw FM, Stapleton HM, Dodson RE, Onasch J, Jazan E, et al. Intervention to reduce gymnast exposure to flame retardants from pit foam: A case study. Environment international. 2019 Jun;127:868–75.
• Kassotis CD, Kollitz EM, Hoffman K, Sosa JA, Stapleton HM. Thyroid receptor antagonism as a contributory mechanism for adipogenesis induced by environmental mixtures in 3T3-L1 cells. The Science of the total environment. 2019 May;666:431–44.
• de Boer J, Stapleton HM. Toward fire safety without chemical risk. Science (New York, NY). 2019 Apr;364(6437):231–2.
• Mitchell CA, Reddam A, Dasgupta S, Zhang S, Stapleton HM, Volz DC. Diphenyl Phosphate-Induced Toxicity During Embryonic Development. Environmental science & technology. 2019 Apr;53(7):3908–16.
• Tuttle AH, Salazar G, Cooper EM, Stapleton HM, Zylka MJ. Choice of vehicle affects pyraclostrobin toxicity in mice. Chemosphere. 2019 Mar;218:501–6.
• Lefevre E, Redfern L, Cooper EM, Stapleton HM, Gunsch CK. Acetate promotes microbial reductive debromination of tetrabromobisphenol A during the startup phase of anaerobic wastewater sludge bioreactors. The Science of the total environment. 2019 Mar;656:959–68.
• Gibson EA, Stapleton HM, Calero L, Holmes D, Burke K, Martinez R, et al. Differential exposure to organophosphate flame retardants in mother-child pairs. Chemosphere. 2019 Mar;219:567–73.
• Doherty BT, Hoffman K, Keil AP, Engel SM, Stapleton HM, Goldman BD, et al. Prenatal exposure to organophosphate esters and cognitive development in young children in the Pregnancy, Infection, and Nutrition Study. Environmental research. 2019 Feb;169:33–40.
• Kassotis CD, Stapleton HM. Endocrine-Mediated Mechanisms of Metabolic Disruption and New Approaches to Examine the Public Health Threat. Frontiers in endocrinology. 2019 Jan;10:39.
• Abdulrahim JW, Stapleton HM, Nguyen M, Kwee LC, Ilkayeva O, Beasley CM, et al. Metabolites Associated With Per- and Polyfluoroalkyl Substance (PFAS) Levels in an Ethnically Diverse Underserved At-Risk Rural Population. In: CIRCULATION. 2019.
• Ruis MT, Baldwin KR, Hall SM, Horman B, Patisaul H, Stapleton HM. Tissue-Specific Accumulation of PBDEs in the Placenta and Effects on Thyroid Regulation. In: INTERNATIONAL JOURNAL OF TOXICOLOGY. SAGE PUBLICATIONS INC; 2019. p. 42–3.
• Gibson EA, Stapleton HM, Calero L, Holmes D, Burke K, Martinez R, et al. Flame retardant exposure assessment: findings from a behavioral intervention study. Journal of exposure science & environmental epidemiology. 2019 Jan;29(1):33–48.
• Messerlian C, Williams PL, Mínguez-Alarcón L, Carignan CC, Ford JB, Butt CM, et al. Organophosphate flame-retardant metabolite concentrations and pregnancy loss among women conceiving with assisted reproductive technology. Fertility and sterility. 2018 Nov;110(6):1137-1144.e1.
• Kassotis CD, Nagel SC, Stapleton HM. Unconventional oil and gas chemicals and wastewater-impacted water samples promote adipogenesis via PPARγ-dependent and independent mechanisms in 3T3-L1 cells. The Science of the total environment. 2018 Nov;640–641:1601–10.
• Stanifer JW, Stapleton HM, Souma T, Wittmer A, Zhao X, Boulware LE. Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review. Clin J Am Soc Nephrol. 2018 Oct 8;13(10):1479–92.
• Hammel SC, Phillips AL, Hoffman K, Stapleton HM. Evaluating the Use of Silicone Wristbands To Measure Personal Exposure to Brominated Flame Retardants. Environmental science & technology. 2018 Oct;52(20):11875–85.
• Kollitz EM, Kassotis CD, Hoffman K, Ferguson PL, Sosa JA, Stapleton HM. Chemical Mixtures Isolated from House Dust Disrupt Thyroid Receptor β Signaling. Environmental science & technology. 2018 Oct;52(20):11857–64.
• Hoffman K, Hammel SC, Phillips AL, Lorenzo AM, Chen A, Calafat AM, et al. Biomarkers of exposure to SVOCs in children and their demographic associations: The TESIE Study. Environment international. 2018 Oct;119:26–36.
• Holzem RM, Stapleton HM, Gunsch CK. Impact of Biosolids on Indigenous Soil Denitrifying Bacteria. Journal of Environmental Engineering (United States). 2018 Sep 1;144(9).
• Bruinstroop E, Dalan R, Cao Y, Bee YM, Chandran K, Cho LW, et al. Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD. J Clin Endocrinol Metab. 2018 Jul 1;103(7):2698–706.
• Phillips AL, Hammel SC, Hoffman K, Lorenzo AM, Chen A, Webster TF, et al. Children's residential exposure to organophosphate ester flame retardants and plasticizers: Investigating exposure pathways in the TESIE study. Environment international. 2018 Jul;116:176–85.
• Hoffman K, Stapleton HM, Lorenzo A, Butt CM, Adair L, Herring AH, et al. Prenatal exposure to organophosphates and associations with birthweight and gestational length. Environment international. 2018 Jul;116:248–54.
• Deziel NC, Yi H, Stapleton HM, Huang H, Zhao N, Zhang Y. A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women. BMC cancer. 2018 Jun;18(1):637.
• Ingle ME, Mínguez-Alarcón L, Carignan CC, Butt CM, Stapleton HM, Williams PL, et al. The association between urinary concentrations of phosphorous-containing flame retardant metabolites and semen parameters among men from a fertility clinic. International journal of hygiene and environmental health. 2018 Jun;221(5):809–15.
• Mitchell CA, Dasgupta S, Zhang S, Stapleton H, Volz DC. Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos. In: BIRTH DEFECTS RESEARCH. WILEY; 2018. p. 785–785.
• Kollitz EM, De Carbonnel L, Stapleton HM, Lee Ferguson P. The Affinity of Brominated Phenolic Compounds for Human and Zebrafish Thyroid Receptor β: Influence of Chemical Structure. Toxicological sciences : an official journal of the Society of Toxicology. 2018 May;163(1):226–39.
• Mitchell CA, Dasgupta S, Zhang S, Stapleton HM, Volz DC. Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos. Toxicological sciences : an official journal of the Society of Toxicology. 2018 May;163(1):307–18.
• Frederiksen M, Stapleton HM, Vorkamp K, Webster TF, Jensen NM, Sørensen JA, et al. Dermal uptake and percutaneous penetration of organophosphate esters in a human skin ex vivo model. Chemosphere. 2018 Apr;197:185–92.
• Bello A, Carignan CC, Xue Y, Stapleton HM, Bello D. Exposure to organophosphate flame retardants in spray polyurethane foam applicators: Role of dermal exposure. Environment international. 2018 Apr;113:55–65.
• Leonetti CP, Butt CM, Stapleton HM. Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo. Chemosphere. 2018 Apr;197:81–8.
• Holzem RM, Gardner CM, Stapleton HM, Gunsch CK. Using laboratory-generated biosolids to evaluate the microbial ecotoxicity of triclosan in a simulated land application scenario. Environmental science and pollution research international. 2018 Apr;25(11):11084–99.
• Kassotis CD, Kollitz EM, Ferguson PL, Stapleton HM. Nonionic Ethoxylated Surfactants Induce Adipogenesis in 3T3-L1 Cells. Toxicological sciences : an official journal of the Society of Toxicology. 2018 Mar;162(1):124–36.
• Carignan CC, Mínguez-Alarcón L, Williams PL, Meeker JD, Stapleton HM, Butt CM, et al. Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization. Environment international. 2018 Feb;111:232–8.
• Rock KD, Horman B, Phillips AL, McRitchie SL, Watson S, Deese-Spruill J, et al. EDC IMPACT: Molecular effects of developmental FM 550 exposure in Wistar rat placenta and fetal forebrain. Endocrine connections. 2018 Feb;7(2):305–24.
• Lefèvre E, Bossa N, Gardner CM, Gehrke GE, Cooper EM, Stapleton HM, et al. Biochar and activated carbon act as promising amendments for promoting the microbial debromination of tetrabromobisphenol A. Water research. 2018 Jan;128:102–10.
• Luz AL, Kassotis CD, Stapleton HM, Meyer JN. The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells. Toxicology. 2018 Jan;393:150–9.
• Phillips A, Stapleton H. Inhibition of Carboxylesterase Enzymes by Isopropylated Triarylphosphate Ester Flame Retardants: Implications for Pharmacotherapy and Cardiovascular Disease. In: INTERNATIONAL JOURNAL OF TOXICOLOGY. SAGE PUBLICATIONS INC; 2018. p. 70–70.
• Castorina R, Bradman A, Stapleton HM, Butt C, Avery D, Harley KG, et al. Current-use flame retardants: Maternal exposure and neurodevelopment in children of the CHAMACOS cohort. Chemosphere. 2017 Dec;189:574–80.
• Phillips AL, Hammel SC, Konstantinov A, Stapleton HM. Characterization of Individual Isopropylated and tert-Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585. Environmental science & technology. 2017 Nov;51(22):13443–9.
• Carignan CC, Mínguez-Alarcón L, Butt CM, Williams PL, Meeker JD, Stapleton HM, et al. Erratum: "Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization". Environmental health perspectives. 2017 Nov;125(11):119001.
• Hoffman K, Lorenzo A, Butt CM, Hammel SC, Henderson BB, Roman SA, et al. Exposure to flame retardant chemicals and occurrence and severity of papillary thyroid cancer: A case-control study. Environment international. 2017 Oct;107:235–42.
• Siebenaler R, Cameron R, Butt CM, Hoffman K, Higgins CP, Stapleton HM. Serum perfluoroalkyl acids (PFAAs) and associations with behavioral attributes. Chemosphere. 2017 Oct;184:687–93.
• Hammel SC, Hoffman K, Lorenzo AM, Chen A, Phillips AL, Butt CM, et al. Associations between flame retardant applications in furniture foam, house dust levels, and residents' serum levels. Environment international. 2017 Oct;107:181–9.
• Thomas MB, Stapleton HM, Dills RL, Violette HD, Christakis DA, Sathyanarayana S. Demographic and dietary risk factors in relation to urinary metabolites of organophosphate flame retardants in toddlers. Chemosphere. 2017 Oct;185:918–25.
• Slotkin TA, Skavicus S, Stapleton HM, Seidler FJ. Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells. Toxicology. 2017 Sep 1;390:32–42.
• Robel AE, Marshall K, Dickinson M, Lunderberg D, Butt C, Peaslee G, et al. Closing the Mass Balance on Fluorine on Papers and Textiles. Environmental science & technology. 2017 Aug;51(16):9022–32.
• Carignan CC, Butt CM, Stapleton HM, Meeker JD, Minguez-Alarcón L, Williams PL, et al. Influence of storage vial material on measurement of organophosphate flame retardant metabolites in urine. Chemosphere. 2017 Aug;181:440–6.
• Carignan CC, Mínguez-Alarcón L, Butt CM, Williams PL, Meeker JD, Stapleton HM, et al. Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization. Environmental health perspectives. 2017 Aug;125(8):087018.
• Baldwin KR, Phillips AL, Horman B, Arambula SE, Rebuli ME, Stapleton HM, et al. Sex Specific Placental Accumulation and Behavioral Effects of Developmental Firemaster 550 Exposure in Wistar Rats. Scientific reports. 2017 Aug;7(1):7118.
• Kassotis CD, Hoffman K, Stapleton HM. Characterization of Adipogenic Activity of House Dust Extracts and Semi-Volatile Indoor Contaminants in 3T3-L1 Cells. Environmental science & technology. 2017 Aug;51(15):8735–45.
• Hoffman K, Gearhart-Serna L, Lorber M, Webster TF, Stapleton HM. Estimated tris(1,3-dichloro-2-propyl) phosphate exposure levels for US infants suggest potential health risks. Environmental science & technology letters. 2017 Aug;4(8):334–8.
• Castorina R, Butt C, Stapleton HM, Avery D, Harley KG, Holland N, et al. Flame retardants and their metabolites in the homes and urine of pregnant women residing in California (the CHAMACOS cohort). Chemosphere. 2017 Jul;179:159–66.
• Smythe TA, Butt CM, Stapleton HM, Pleskach K, Ratnayake G, Song CY, et al. Impacts of Unregulated Novel Brominated Flame Retardants on Human Liver Thyroid Deiodination and Sulfotransferation. Environmental science & technology. 2017 Jun;51(12):7245–53.
• Preston EV, McClean MD, Claus Henn B, Stapleton HM, Braverman LE, Pearce EN, et al. Associations between urinary diphenyl phosphate and thyroid function. Environment international. 2017 Apr;101:158–64.
• Hoffman K, Butt CM, Webster TF, Preston EV, Hammel SC, Makey C, et al. Temporal Trends in Exposure to Organophosphate Flame Retardants in the United States. Environ Sci Technol Lett. 2017 Mar 14;4(3):112–8.
• Ferguson PL, Stapleton HM. Comment on "Mutagenic Azo Dyes, Rather Than Flame Retardants, Are the Predominant Brominated Compounds in House Dust". Environmental science & technology. 2017 Mar;51(6):3588–90.
• Hoffman K, Webster TF, Sjödin A, Stapleton HM. Toddler's behavior and its impacts on exposure to polybrominated diphenyl ethers. Journal of exposure science & environmental epidemiology. 2017 Mar;27(2):193–7.
• Cowell WJ, Stapleton HM, Holmes D, Calero L, Tobon C, Perzanowski M, et al. Prevalence of historical and replacement brominated flame retardant chemicals in New York City homes. Emerging contaminants. 2017 Mar;3(1):32–9.
• Kassotis CD, Masse L, Kim S, Schlezinger JJ, Webster TF, Stapleton HM. Characterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling. Scientific reports. 2017 Feb;7:42104.
• Lewis JJ, Hollingsworth JW, Chartier RT, Cooper EM, Foster WM, Gomes GL, et al. Biogas Stoves Reduce Firewood Use, Household Air Pollution, and Hospital Visits in Odisha, India. Environ Sci Technol. 2017 Jan 3;51(1):560–9.
• Hoffman K, Lorenzo A, Butt CM, Adair L, Herring AH, Stapleton HM, et al. Predictors of urinary flame retardant concentration among pregnant women. Environment international. 2017 Jan;98:96–101.
• Macaulay LJ, Chernick M, Chen A, Hinton DE, Bailey JM, Kullman SW, et al. Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development. Environ Toxicol Chem. 2017 Jan;36(1):36–48.
• Soubry A, Hoyo C, Butt CM, Fieuws S, Price TM, Murphy SK, et al. Human exposure to flame-retardants is associated with aberrant DNA methylation at imprinted genes in sperm. Environ Epigenet. 2017 Jan;3(1):dvx003.
• Hoffman K, Sosa JA, Stapleton HM. Do flame retardant chemicals increase the risk for thyroid dysregulation and cancer? Current opinion in oncology. 2017 Jan;29(1):7–13.
• Leonetti C, Butt CM, Hoffman K, Hammel SC, Miranda ML, Stapleton HM. Brominated flame retardants in placental tissues: associations with infant sex and thyroid hormone endpoints. Environmental health : a global access science source. 2016 Nov;15(1):113.
• Phillips AL, Chen A, Rock KD, Horman B, Patisaul HB, Stapleton HM. Editor's Highlight: Transplacental and Lactational Transfer of Firemaster® 550 Components in Dosed Wistar Rats. Toxicological sciences : an official journal of the Society of Toxicology. 2016 Oct;153(2):246–57.
• Cooper EM, Kroeger G, Davis K, Clark CR, Ferguson PL, Stapleton HM. Results from Screening Polyurethane Foam Based Consumer Products for Flame Retardant Chemicals: Assessing Impacts on the Change in the Furniture Flammability Standards. Environmental science & technology. 2016 Oct;50(19):10653–60.
• Carignan CC, Fang M, Stapleton HM, Heiger-Bernays W, McClean MD, Webster TF. Urinary biomarkers of flame retardant exposure among collegiate U.S. gymnasts. Environment international. 2016 Sep;94:362–8.
• Butt CM, Hoffman K, Chen A, Lorenzo A, Congleton J, Stapleton HM. Regional comparison of organophosphate flame retardant (PFR) urinary metabolites and tetrabromobenzoic acid (TBBA) in mother-toddler pairs from California and New Jersey. Environment international. 2016 Sep;94:627–34.
• Hammel SC, Hoffman K, Webster TF, Anderson KA, Stapleton HM. Correction to Measuring Personal Exposure to Organophosphate Flame Retardants using Silicone Wristbands and Hand Wipes. Environmental science & technology. 2016 Sep;50(18):10291.
• Volz DC, Leet JK, Chen A, Stapleton HM, Katiyar N, Kaundal R, et al. Tris(1,3-dichloro-2-propyl)phosphate Induces Genome-Wide Hypomethylation within Early Zebrafish Embryos. Environmental science & technology. 2016 Sep;50(18):10255–63.
• Gomes G, Ward P, Lorenzo A, Hoffman K, Stapleton HM. Characterizing Flame Retardant Applications and Potential Human Exposure in Backpacking Tents. Environmental science & technology. 2016 May;50(10):5338–45.
• Butt CM, Miranda ML, Stapleton HM. Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum. Analytical and bioanalytical chemistry. 2016 Apr;408(10):2449–59.
• Su G, Letcher RJ, Yu H, Gooden DM, Stapleton HM. Determination of glucuronide conjugates of hydroxyl triphenyl phosphate (OH-TPHP) metabolites in human urine and its use as a biomarker of TPHP exposure. Chemosphere. 2016 Apr;149:314–9.
• Hammel SC, Hoffman K, Webster TF, Anderson KA, Stapleton HM. Measuring Personal Exposure to Organophosphate Flame Retardants Using Silicone Wristbands and Hand Wipes. Environmental science & technology. 2016 Apr;50(8):4483–91.
• Leonetti C, Butt CM, Hoffman K, Miranda ML, Stapleton HM. Concentrations of polybrominated diphenyl ethers (PBDEs) and 2,4,6-tribromophenol in human placental tissues. Environment international. 2016 Mar;88:23–9.
• Czaplicki LM, Cooper E, Ferguson PL, Stapleton HM, Vilgalys R, Gunsch CK. A New Perspective on Sustainable Soil Remediation-Case Study Suggests Novel Fungal Genera Could Facilitate in situ Biodegradation of Hazardous Contaminants. Remediation (New York, NY). 2016 Jan;26(2):59–72.
• Lefevre E, Cooper E, Stapleton HM, Gunsch CK. Characterization and Adaptation of Anaerobic Sludge Microbial Communities Exposed to Tetrabromobisphenol A. PloS one. 2016 Jan;11(7):e0157622.
• Mendelsohn E, Hagopian A, Hoffman K, Butt CM, Lorenzo A, Congleton J, et al. Nail polish as a source of exposure to triphenyl phosphate. Environment international. 2016 Jan;86:45–51.
• Hoffman K, Butt CM, Chen A, Limkakeng AT, Stapleton HM. High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products. Environ Sci Technol. 2015 Dec 15;49(24):14554–9.
• Miranda ML, Anthopolos R, Wolkin A, Stapleton HM. Associations of birth outcomes with maternal polybrominated diphenyl ethers and thyroid hormones during pregnancy. Environment international. 2015 Dec;85:244–53.
• Macaulay LJ, Chen A, Rock KD, Dishaw LV, Dong W, Hinton DE, et al. Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β. Aquatic toxicology (Amsterdam, Netherlands). 2015 Nov;168:38–47.
• Maley AM, Falk KA, Hoover L, Earlywine EB, Seymour MD, Deyoung PA, et al. Detection of halogenated flame retardants in polyurethane foam by particle induced X-ray emission. Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 2015 Sep 1;358:21–5.
• Fang M, Webster TF, Stapleton HM. Effect-Directed Analysis of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) Ligands in Indoor Dust. Environmental science & technology. 2015 Aug;49(16):10065–73.
• Fang M, Webster TF, Stapleton HM. Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust. Environmental science & technology. 2015 Aug;49(16):10057–64.
• Scanlan LD, Loguinov AV, Teng Q, Antczak P, Dailey KP, Nowinski DT, et al. Gene transcription, metabolite and lipid profiling in eco-indicator daphnia magna indicate diverse mechanisms of toxicity by legacy and emerging flame-retardants. Environmental science & technology. 2015 Jun;49(12):7400–10.
• Roberts SC, Bianco AC, Stapleton HM. Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers. Chemical research in toxicology. 2015 Jun;28(6):1265–74.
• Dishaw L, Stapleton H. Halogenated organophosphate flame retardants: Developmental neurotoxicity and possible mechanisms of action. In: Neurotoxicology and Teratology. Elsevier BV; 2015. p. 106–106.
• Davis EF, Gunsch CK, Stapleton HM. Fate of flame retardants and the antimicrobial agent triclosan in planted and unplanted biosolid-amended soils. Environmental toxicology and chemistry. 2015 May;34(5):968–76.
• Su G, Letcher RJ, Crump D, Gooden DM, Stapleton HM. In vitro metabolism of the flame retardant triphenyl phosphate in chicken embryonic hepatocytes and the importance of the hydroxylation pathway. Environmental Science and Technology Letters. 2015 Apr 14;2(4):100–4.
• Isales GM, Hipszer RA, Raftery TD, Chen A, Stapleton HM, Volz DC. Triphenyl phosphate-induced developmental toxicity in zebrafish: potential role of the retinoic acid receptor. Aquatic toxicology (Amsterdam, Netherlands). 2015 Apr;161:221–30.
• Leonetti C, Neufeld T, Butt C, Stapleton H. Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants in a human choriocarcinoma cell line, BeWo. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. AMER CHEMICAL SOC; 2015.
• Fang M, Webster TF, Ferguson PL, Stapleton HM. Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust. Environmental health perspectives. 2015 Feb;123(2):166–72.
• Hoffman K, Garantziotis S, Birnbaum LS, Stapleton HM. Monitoring indoor exposure to organophosphate flame retardants: hand wipes and house dust. Environmental health perspectives. 2015 Feb;123(2):160–5.
• Freitag AR, Thayer LAR, Leonetti C, Stapleton HM, Hamlin HJ. Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar. Aquaculture. 2015 Jan 1;436:8–12.
• Fang M, Webster TF, Ferguson PL, Stapleton HM. Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust. Environmental Health Perspectives. 2015 Jan 1;123(2):166–72.
• Macaulay LJ, Bailey JM, Levin ED, Stapleton HM. Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior. Neurotoxicol Teratol. 2015;52(Pt B):119–26.
• McIntyre RL, Kenerson HL, Subramanian S, Wang SA, Kazami M, Stapleton HM, et al. Polybrominated diphenyl ether congener, BDE-47, impairs insulin sensitivity in mice with liver-specific Pten deficiency. BMC obesity. 2015 Jan;2:3.
• Dishaw LV, Macaulay LJ, Roberts SC, Stapleton HM. Exposures, mechanisms, and impacts of endocrine-active flame retardants. Current opinion in pharmacology. 2014 Dec;19:125–33.
• Stapleton HM, Misenheimer J, Hoffman K, Webster TF. Flame retardant associations between children's handwipes and house dust. Chemosphere. 2014 Dec;116:54–60.
• Fang M, Getzinger GJ, Cooper EM, Clark BW, Garner LVT, Di Giulio RT, et al. Effect-directed analysis of Elizabeth River porewater: developmental toxicity in zebrafish (Danio rerio). Environmental toxicology and chemistry. 2014 Dec;33(12):2767–74.
• Dishaw LV, Hunter DL, Padnos B, Padilla S, Stapleton HM. Developmental exposure to organophosphate flame retardants elicits overt toxicity and alters behavior in early life stage zebrafish (Danio rerio). Toxicological sciences : an official journal of the Society of Toxicology. 2014 Dec;142(2):445–54.
• Pillai HK, Fang M, Beglov D, Kozakov D, Vajda S, Stapleton HM, et al. Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro. Environmental health perspectives. 2014 Nov;122(11):1225–32.
• Fang M, Stapleton HM. Evaluating the bioaccessibility of flame retardants in house dust using an in vitro Tenax bead-assisted sorptive physiologically based method. Environmental science & technology. 2014 Nov;48(22):13323–30.
• Holzem RM, Stapleton HM, Gunsch CK. Response to comment on "Determining the ecological impacts of organic contaminants in biosolids using a high-throughput colorimetric denitrification assay: a case study with antimicrobial agents". Environmental science & technology. 2014 Oct;48(20):12470–1.
• Martin NP, Marron Fernandez de Velasco E, Mizuno F, Scappini EL, Gloss B, Erxleben C, et al. A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo. Endocrinology. 2014 Sep;155(9):3713–24.
• Hoffman K, Fang M, Horman B, Patisaul HB, Garantziotis S, Birnbaum LS, et al. Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550. Environmental health perspectives. 2014 Sep;122(9):963–9.
• Butt CM, Congleton J, Hoffman K, Fang M, Stapleton HM. Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers. Environmental science & technology. 2014 Sep;48(17):10432–8.
• Belcher SM, Cookman CJ, Patisaul HB, Stapleton HM. In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components. Toxicology letters. 2014 Jul;228(2):93–102.
• Wolf CJ, Fang M, Stapleton HM, Abbott BD. Activation of Human Peroxisome Proliferator-Activated Receptor-Gamma (PPAR gamma) by House Dust Extracts. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY. 2014 May 1;100(5):393–393.
• Hoffman K, Daniels JL, Stapleton HM. Urinary metabolites of organophosphate flame retardants and their variability in pregnant women. Environment international. 2014 Feb;63:169–72.
• Keller AS, Raju NP, Webster TF, Stapleton HM. Flame Retardant Applications in Camping Tents and Potential Exposure. Environmental science & technology letters. 2014 Feb;1(2):152–5.
• Muzzio AM, Noyes PD, Stapleton HM, Lema SC. Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish. Comparative biochemistry and physiology Part A, Molecular & integrative physiology. 2014 Jan;167:77–89.
• Noyes PD, Lema SC, Roberts SC, Cooper EM, Stapleton HM. Rapid method for the measurement of circulating thyroid hormones in low volumes of teleost fish plasma by LC-ESI/MS/MS. Analytical and bioanalytical chemistry. 2014 Jan;406(3):715–26.
• Dong W, Macaulay LJ, Kwok KW, Hinton DE, Ferguson PL, Stapleton HM. The PBDE metabolite 6-OH-BDE 47 affects melanin pigmentation and THRβ MRNA expression in the eye of zebrafish embryos. Endocrine disruptors (Austin, Tex). 2014 Jan;2(1):e969072.
• Holzem RM, Stapleton HM, Gunsch CK. Determining the ecological impacts of organic contaminants in biosolids using a high-throughput colorimetric denitrification assay: a case study with antimicrobial agents. Environmental science & technology. 2014 Jan;48(3):1646–55.
• Noyes PD, Stapleton HM. PBDE flame retardants: Toxicokinetics and thyroid hormone endocrine disruption in fish. Endocrine Disruptors. 2014 Jan 1;2(1):e29430-1-e29430-25.
• Levin ED, Cauley M, Johnson JE, Cooper EM, Stapleton HM, Ferguson PL, et al. Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor. Neurotoxicol Teratol. 2014;41:35–42.
• Carignan CC, Heiger-Bernays W, McClean MD, Roberts SC, Stapleton HM, Sjödin A, et al. Flame retardant exposure among collegiate United States gymnasts. Environmental science & technology. 2013 Dec;47(23):13848–56.
• Butt CM, Stapleton HM. Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics. Chemical research in toxicology. 2013 Nov;26(11):1692–702.
• Meeker JD, Cooper EM, Stapleton HM, Hauser R. Exploratory analysis of urinary metabolites of phosphorus-containing flame retardants in relation to markers of male reproductive health. Endocrine disruptors (Austin, Tex). 2013 Oct;1(1):e26306.
• Watkins DJ, McClean MD, Fraser AJ, Weinberg J, Stapleton HM, Webster TF. Associations between PBDEs in office air, dust, and surface wipes. Environment international. 2013 Sep;59:124–32.
• Clark BW, Cooper EM, Stapleton HM, Di Giulio RT. Compound- and mixture-specific differences in resistance to polycyclic aromatic hydrocarbons and PCB-126 among Fundulus heteroclitus subpopulations throughout the Elizabeth River estuary (Virginia, USA). Environmental science & technology. 2013 Sep;47(18):10556–66.
• Noyes PD, Lema SC, Macaulay LJ, Douglas NK, Stapleton HM. Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows. Environmental science & technology. 2013 Sep;47(17):10012–21.
• Slotkin TA, Cooper EM, Stapleton HM, Seidler FJ. Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos? Environ Toxicol Pharmacol. 2013 Sep;36(2):284–7.
• Lohmann R, Stapleton HM, Hites RA. Science In TSCA Reform. CHEMICAL & ENGINEERING NEWS. 2013 Aug 12;91(32):3–3.
• Lohmann R, Stapleton HM, Hites RA. Science should guide TSCA reform. Environmental science & technology. 2013 Aug;47(16):8995–6.
• McGee SP, Konstantinov A, Stapleton HM, Volz DC. Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor. Toxicological sciences : an official journal of the Society of Toxicology. 2013 May;133(1):144–56.
• Meeker JD, Cooper EM, Stapleton HM, Hauser R. Urinary metabolites of organophosphate flame retardants: temporal variability and correlations with house dust concentrations. Environmental health perspectives. 2013 May;121(5):580–5.
• Fang M, Webster TF, Gooden D, Cooper EM, McClean MD, Carignan C, et al. Investigating a novel flame retardant known as V6: measurements in baby products, house dust, and car dust. Environmental science & technology. 2013 May;47(9):4449–54.
• Carignan CC, McClean MD, Cooper EM, Watkins DJ, Fraser AJ, Heiger-Bernays W, et al. Predictors of tris(1,3-dichloro-2-propyl) phosphate metabolite in the urine of office workers. Environment international. 2013 May;55:56–61.
• Dong W, Macaulay LJ, Kwok KWH, Hinton DE, Stapleton HM. Using whole mount in situ hybridization to examine thyroid hormone deiodinase expression in embryonic and larval zebrafish: a tool for examining OH-BDE toxicity to early life stages. Aquatic toxicology (Amsterdam, Netherlands). 2013 May;132–133:190–9.
• Bailey J, Oliveri A, Stapleton H, Levin E. Behavioral effects of short-term exposure to Firemaster 550. In: Neurotoxicology and Teratology. Elsevier BV; 2013. p. 86–86.
• Webster TF, Stapleton HM. Human exposure assessment of indoor dust: Webster and Stapleton respond. Environmental health perspectives. 2013 Apr 1;121(4).
• Muzzio AM, Noyes PD, Stapleton HM, Lema SC. The Organic Anion Transporting Protein (OATP) Family in a Teleost Fish Model. In: INTEGRATIVE AND COMPARATIVE BIOLOGY. OXFORD UNIV PRESS INC; 2013. p. E340–E340.
• Webster TF, Stapleton HM. Human exposure assessment of indoor dust: Webster and Stapleton respond. Environmental health perspectives. 2013 Apr;121(4):A110–1.
• Patisaul HB, Roberts SC, Mabrey N, McCaffrey KA, Gear RB, Braun J, et al. Accumulation and endocrine disrupting effects of the flame retardant mixture Firemaster® 550 in rats: an exploratory assessment. Journal of biochemical and molecular toxicology. 2013 Feb;27(2):124–36.
• Allen JG, Stapleton HM, Vallarino J, McNeely E, McClean MD, Harrad SJ, et al. Exposure to flame retardant chemicals on commercial airplanes. Environmental health : a global access science source. 2013 Feb;12:17.
• Webster TF, Stapleton HM, McClean MD. Exposure to Polybrominated Diphenyl Ethers in the Indoor Environment. Fire Technology. 2013;1–11.
• Collins TJ, de Wit C, Mulvihill MJ, Roberts DH, Rudel R, Sedlak D, et al. OBSERVATIONS ON FLAME RETARDANTS ARTICLES. CHEMICAL & ENGINEERING NEWS. 2012 Dec 17;90(51):4–5.
• Springer C, Dere E, Hall SJ, McDonnell EV, Roberts SC, Butt CM, et al. Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dust. Environmental health perspectives. 2012 Dec;120(12):1711–9.
• Stapleton HM, Sharma S, Getzinger G, Ferguson PL, Gabriel M, Webster TF, et al. Novel and high volume use flame retardants in US couches reflective of the 2005 PentaBDE phase out. Environmental science & technology. 2012 Dec;46(24):13432–9.
• McGee SP, Cooper EM, Stapleton HM, Volz DC. Early zebrafish embryogenesis is susceptible to developmental TDCPP exposure. Environmental health perspectives. 2012 Nov;120(11):1585–91.
• Bearr JS, Mitchelmore CL, Roberts SC, Stapleton HM. Species specific differences in the in vitro metabolism of the flame retardant mixture, Firemaster® BZ-54. Aquatic toxicology (Amsterdam, Netherlands). 2012 Nov;124–125:41–7.
• Klosterhaus SL, Stapleton HM, La Guardia MJ, Greig DJ. Brominated and chlorinated flame retardants in San Francisco Bay sediments and wildlife. Environment international. 2012 Oct;47:56–65.
• Ashley JTF, Vasquez MA, Zelanko P, McKinley E, Schafer M, Zaoudeh L, et al. Trophic transfer of polybrominated diphenyl ethers and polychlorinated biphenyls in a tidal freshwater marsh. Chemistry and Ecology. 2012 Aug 1;28(4):305–25.
• Stapleton HM, Eagle S, Sjödin A, Webster TF. Serum PBDEs in a North Carolina toddler cohort: associations with handwipes, house dust, and socioeconomic variables. Environmental health perspectives. 2012 Jul;120(7):1049–54.
• Roberts SC, Macaulay LJ, Stapleton HM. In vitro metabolism of the brominated flame retardants 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (TBPH) in human and rat tissues. Chemical research in toxicology. 2012 Jul;25(7):1435–41.
• Watkins DJ, McClean MD, Fraser AJ, Weinberg J, Stapleton HM, Sjoedin A. Exposure to polybrominated diphenyl ethers (PBDEs) in offices. ENVIRONNEMENT RISQUES & SANTE. 2012 Jul 1;11(4):274–5.
• Davis EF, Klosterhaus SL, Stapleton HM. Measurement of flame retardants and triclosan in municipal sewage sludge and biosolids. Environment international. 2012 Apr;40:1–7.
• Webster TF, Stapleton HM. Flame Retardants: Polybrominated Diphenyl Ethers and their Replacements. 2012 Mar 30;89–108.
• McClain V, Stapleton HM, Tilton F, Gallagher EP. BDE 49 and developmental toxicity in zebrafish. Comparative biochemistry and physiology Toxicology & pharmacology : CBP. 2012 Mar;155(2):253–8.
• Johnson PJ, Stapleton HM, Mukherjee B, Hauser R, Meeker JD. Associations between brominated flame retardants in house dust and hormone levels in men. (Accepted) Sci Total Environ. 2012;
• Buttke DE, Wolkin A, Stapleton HM, Miranda ML. Associations between serum levels of Polybrominated Diphenyl Ether (PBDE) flame retardants and environmental and behavioral factors in pregnant women. Journal of Exposure Science and Environmental Epidemiology. 2012;
• Watkins DJ, McClean MD, Fraser AJ, Weinberg J, Stapleton HM, Sjödin A, et al. Impact of dust from multiple microenvironments and diet on PentaBDE body burden. Environmental science & technology. 2012 Jan;46(2):1192–200.
• McGee SP, Cooper E, Stapleton HM, Volz D. Early Zebrafish Embryogenesis Is Susceptible to Developmental TDCPP Exposure. Environmental Health Perspectives. 2012;120(11):1586–91.
• Fraser AJ, Webster TF, Watkins DJ, Nelson JW, Stapleton HM, Calafat AM, et al. Polyfluorinated compounds in serum linked to indoor air in office environments. Environmental science & technology. 2012 Jan;46(2):1209–15.
• Butt CM, Wang D, Stapleton HM. Halogenated phenolic contaminants inhibit the in vitro activity of the thyroid-regulating deiodinases in human liver. Toxicological sciences : an official journal of the Society of Toxicology. 2011 Dec;124(2):339–47.
• Dishaw LV, Powers CM, Ryde IT, Roberts SC, Seidler FJ, Slotkin TA, et al. Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. Toxicol Appl Pharmacol. 2011 Nov 1;256(3):281–9.
• Jung D, Matson CW, Collins LB, Laban G, Stapleton HM, Bickham JW, et al. Genotoxicity in Atlantic killifish (Fundulus heteroclitus) from a PAH-contaminated Superfund site on the Elizabeth River, Virginia. Ecotoxicology (London, England). 2011 Nov;20(8):1890–9.
• Cooper EM, Covaci A, van Nuijs ALN, Webster TF, Stapleton HM. Analysis of the flame retardant metabolites bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and diphenyl phosphate (DPP) in urine using liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry. 2011 Oct;401(7):2123–32.
• Watkins DJ, McClean MD, Fraser AJ, Weinberg J, Stapleton HM, Sjödin A, et al. Exposure to PBDEs in the office environment: evaluating the relationships between dust, handwipes, and serum. Environmental health perspectives. 2011 Sep;119(9):1247–52.
• Noyes PD, Hinton DE, Stapleton HM. Accumulation and debromination of decabromodiphenyl ether (BDE-209) in juvenile fathead minnows (Pimephales promelas) induces thyroid disruption and liver alterations. Toxicological sciences : an official journal of the Society of Toxicology. 2011 Aug;122(2):265–74.
• Stapleton HM, Klosterhaus S, Keller A, Ferguson PL, van Bergen S, Cooper E, et al. Identification of flame retardants in polyurethane foam collected from baby products. Environmental science & technology. 2011 Jun;45(12):5323–31.
• Roberts SC, Noyes PD, Gallagher EP, Stapleton HM. Species-specific differences and structure-activity relationships in the debromination of PBDE congeners in three fish species. Environmental science & technology. 2011 Mar;45(5):1999–2005.
• Stapleton HM, Eagle SD, Sjodin A, Webster TF. Serum PBDEs in US Toddlers: Associations with Hand Wipes, House Dust and Socioeconomic Variables (Submitted). Environmental Health Perspectives. 2011;
• Stapleton HM, Eagle S, Anthopolos R, Wolkin A, Miranda ML. Associations between Polybrominated Diphenyl Ether (PBDE) Flame Retardants, Phenolic Metabolites, and Thyroid Hormones during Pregnancy. Environmental Health Perspectives. 2011;119(10):1454–9.
• Tomy GT, Palace V, Marvin C, Stapleton HM, Covaci A, Harrad S. Biotransformation of HBCD in biological systems can confound temporal-trend studies. Environmental science & technology. 2011 Jan;45(2):364–5.
• Webster T, Stapleton H, McClean M. Exposure to Polybrominated Diphenyl Ethers in Indoor Environments. In: Epidemiology. Ovid Technologies (Wolters Kluwer Health); 2011. p. S117–S117.
• Cooper EM, Stapleton HM, Matson CW, Di Giulio RT, Schuler AJ. Ultraviolet treatment and biodegradation of dibenzothiophene: Identification and toxicity of products. Environmental toxicology and chemistry. 2010 Nov;29(11):2409–16.
• Ashley JTF, Ward JS, Schafer MW, Stapleton HM, Velinsky DJ. Evaluating daily exposure to polychlorinated biphenyls and polybrominated diphenyl ethers in fish oil supplements. Food additives & contaminants Part A, Chemistry, analysis, control, exposure & risk assessment. 2010 Aug;27(8):1177–85.
• Wang D, Stapleton HM. Analysis of thyroid hormones in serum by liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry. 2010 Jul;397(5):1831–9.
• Johnson PI, Stapleton HM, Sjodin A, Meeker JD. Relationships between polybrominated diphenyl ether concentrations in house dust and serum. Environmental science & technology. 2010 Jul;44(14):5627–32.
• Kim GB, Stapleton HM. PBDEs, methoxylated PBDEs and HBCDs in Japanese common squid (Todarodes pacificus) from Korean offshore waters. Marine pollution bulletin. 2010 Jun;60(6):935–40.
• Noyes PD, Kelly SM, Mitchelmore CL, Stapleton HM. Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp. Aquatic toxicology (Amsterdam, Netherlands). 2010 Apr;97(2):142–50.
• Meeker JD, Stapleton HM. House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters. Environmental health perspectives. 2010 Mar;118(3):318–23.
• Bearr JS, Stapleton HM, Mitchelmore CL. Accumulation and DNA damage in fathead minnows (Pimephales promelas) exposed to 2 brominated flame-retardant mixtures, Firemaster 550 and Firemaster BZ-54. Environmental toxicology and chemistry. 2010 Mar;29(3):722–9.
• Johnson PI, Stapleton HM, Hauser R, Meeker JD. Relationships Between Brominated Flame Retardant Concentrations in House Dust and Serum Hormone Levels in Men. In: Epidemiology. Ovid Technologies (Wolters Kluwer Health); 2009. p. S162–3.
• Stapleton HM, Davis EF. Response to "Comment on 'Photodegradation Pathways of Nonabrominated Diphenyl Ethers, 2-Ethylhexyltetrabromobenzoate, and Di(2-ethylhexyl)tetrabromophthalate: Identifying Potential Markers of Photodegradation'". Environmental science & technology. 2009 Oct;43(20):7994.
• Stapleton HM, Klosterhaus S, Eagle S, Fuh J, Meeker JD, Blum A, et al. Detection of organophosphate flame retardants in furniture foam and U.S. house dust. Environmental science & technology. 2009 Oct;43(19):7490–5.
• Davis EF, Stapleton HM. Photodegradation pathways of nonabrominated diphenyl ethers, 2-ethylhexyltetrabromobenzoate and di(2-ethylhexyl)tetrabromophthalate: identifying potential markers of photodegradation. Environmental science & technology. 2009 Aug;43(15):5739–46.
• Browne EP, Stapleton HM, Kelly SM, Tilton SC, Gallagher EP. In vitro hepatic metabolism of 2,2',4,4',5-pentabromodiphenyl ether (BDE 99) in Chinook salmon (Onchorhynchus tshawytscha). Aquatic toxicology (Amsterdam, Netherlands). 2009 May;92(4):281–7.
• Webster TF, Harrad S, Millette JR, Holbrook RD, Davis JM, Stapleton HM, et al. Identifying transfer mechanisms and sources of decabromodiphenyl ether (BDE 209) in indoor environments using environmental forensic microscopy. Environmental science & technology. 2009 May;43(9):3067–72.
• Stapleton HM, Kelly SM, Pei R, Letcher RJ, Gunsch C. Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro. Environmental health perspectives. 2009 Feb;117(2):197–202.
• Stapleton HM, Kelly SM, Allen JG, Watkins DJ, Heiger-Bernays WJ, McClean MD, et al. Response to comment on "Altemate and new brominated flame retardants detected in U.S. house dust". Environmental Science and Technology. 2008 Dec 15;42(24):9455–6.
• Allen JG, McClean MD, Stapleton HM, Webster TF. Critical factors in assessing exposure to PBDEs via house dust. Environment international. 2008 Nov;34(8):1085–91.
• Allen JG, McClean MD, Stapleton HM, Webster TF. Televisions as Sources of DecaBDE in House Dust. In: EPIDEMIOLOGY. LIPPINCOTT WILLIAMS & WILKINS; 2008. p. S76–S76.
• Huwe JK, Hakk H, Stapleton HM, Birnbaum LS. Tissue Distribution of Polybrominated Diphenyl Ethers in Rats Following Oral Exposure and the Relationship to Body Burdens. In: EPIDEMIOLOGY. LIPPINCOTT WILLIAMS & WILKINS; 2008. p. S76–S76.
• Stapleton HM, Allen JG, Kelly SM, Konstantinov A, Klosterhaus S, Watkins D, et al. Alternate and new brominated flame retardants detected in U.S. house dust. Environmental science & technology. 2008 Sep;42(18):6910–6.
• Allen JG, McClean MD, Stapleton HM, Webster TF. Linking PBDEs in house dust to consumer products using X-ray fluorescence. Environmental science & technology. 2008 Jun;42(11):4222–8.
• Stapleton HM, Sjödin A, Jones RS, Niehüser S, Zhang Y, Patterson DG. Serum levels of polybrominated diphenyl ethers (PBDEs) in foam recyclers and carpet installers working in the United States. Environmental science & technology. 2008 May;42(9):3453–8.
• Stapleton HM, Kelly SM, Allen JG, Mcclean MD, Webster TF. Measurement of polybrominated diphenyl ethers on hand wipes: estimating exposure from hand-to-mouth contact. Environmental science & technology. 2008 May;42(9):3329–34.
• Huwe JK, Hakk H, Smith DJ, Diliberto JJ, Richardson V, Stapleton HM, et al. Comparative absorption and bioaccumulation of polybrominated diphenyl ethers following ingestion via dust and oil in male rats. Environmental science & technology. 2008 Apr;42(7):2694–700.
• Stapleton HM, Dodder NG. Photodegradation of decabromodiphenyl ether in house dust by natural sunlight. Environmental toxicology and chemistry. 2008 Feb;27(2):306–12.
• Stapleton HM, Kelly SM, Allen JG, McClean MD, Webster TF. Measurement of Polybrominated Diphenyl Ethers on Hand Wipes: Estimating Exposure from Hand to Mouth Contact. Environ Sci & Technol. 2008;49(9):3329–34.
• Allen JG, McClean MD, Stapleton HM, Webster TF. Longitudinal Analysis of Polybrominated Diphenyl Ethers (PBDEs) in Household Microenvironments: Characterization of Dust and Relationship to Indoor Air. Environment International. 2008;34(8):1085–91.
• Stapleton HM, Sjodin A, Jones RS, Niehauser S, Zhang Y, Patterson DG. Serum PBDE Levels in Occupationally Exposed Individuals in the United States. Environ Sci & Technol. 2008;42(9):3453–8.
• Benedict RT, Stapleton HM, Letcher RJ, Mitchelmore CL. Debromination of polybrominated diphenyl ether-99 (BDE-99) in carp (Cyprinus carpio) microflora and microsomes. Chemosphere. 2007 Oct;69(6):987–93.
• Schantz MM, Keller JM, Leigh S, Patterson DG, Sharpless KE, Sjödin A, et al. Certification of SRM 1589a PCBs, pesticides, PBDEs, and dioxins/furans in human serum. Analytical and bioanalytical chemistry. 2007 Oct;389(4):1201–8.
• Schantz BMM, Keller JM, Kucklick JR, Poster DL, Stapleton HM, Pol SSV, et al. New standard reference material (srm) 2585: Organic contaminants in house dust to support exposure assessment measurements. American Laboratory. 2007 Aug 1;39(15):22–8.
• Ashley JTF, Libero D, Halscheid E, Zaoudeh L, Stapleton HM. Polybrominated diphenyl ethers in American eels (Anguilla rostrata) from the Delaware River, USA. Bulletin of environmental contamination and toxicology. 2007 Jul;79(1):99–103.
• Allen JG, McClean MD, Stapleton HM, Nelson JW, Webster TF. Personal exposure to polybrominated diphenyl ethers (PBDEs) in residential indoor air. Environmental science & technology. 2007 Jul;41(13):4574–9.
• Stapleton HM, Keller JM, Schantz MM, Kucklick JR, Leigh SD, Wise SA. Determination of polybrominated diphenyl ethers in environmental standard reference materials. Analytical and bioanalytical chemistry. 2007 Apr;387(7):2365–79.
• Allen J, Mcclean M, Stapleton H, Nelson J, Sanchez G, Fraser A, et al. PBDE Levels in Indoor Air and Dust Collected From US Urban Residences. In: Epidemiology. Ovid Technologies (Wolters Kluwer Health); 2006. p. S375–S375.
• Stapleton HM. Instrumental methods and challenges in quantifying polybrominated diphenyl ethers in environmental extracts: a review. Analytical and bioanalytical chemistry. 2006 Oct;386(4):807–17.
• Stapleton HM, Brazil B, Holbrook RD, Mitchelmore CL, Benedict R, Konstantinov A, et al. In vivo and in vitro debromination of decabromodiphenyl ether (BDE 209) by juvenile rainbow trout and common carp. Environmental science & technology. 2006 Aug;40(15):4653–8.
• Stapleton HM, Dodder NG, Kucklick JR, Reddy CM, Schantz MM, Becker PR, et al. Determination of HBCD, PBDEs and MeO-BDEs in California sea lions (Zalophus californianus) stranded between 1993 and 2003. Marine pollution bulletin. 2006 May;52(5):522–31.
• Stapleton HM, Harner T, Shoeib M, Keller JM, Schantz MM, Leigh SD, et al. Determination of polybrominated diphenyl ethers in indoor dust standard reference materials. Analytical and bioanalytical chemistry. 2006 Feb;384(3):791–800.
• Schantz MM, Kucklick JR, Poster D, Stapleton HM, Wise SA. Certification of a house dust standard reference material for determination of organic contaminants. In: ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY. AMER CHEMICAL SOC; 2005. p. U209–U209.
• Stapleton HM, Dodder NG, Offenberg JH, Schantz MM, Wise SA. Polybrominated diphenyl ethers in house dust and clothes dryer lint. Environmental science & technology. 2005 Feb;39(4):925–31.
• Tuerk KJS, Kucklick JR, Becker PR, Stapleton HM, Baker JE. Persistent organic pollutants in two dolphin species with focus on toxaphene and polybrominated diphenyl ethers. Environmental science & technology. 2005 Feb;39(3):692–8.
• Stapleton HM, Letcher RJ, Li J, Baker JE. Dietary accumulation and metabolism of polybrominated diphenyl ethers by juvenile carp (Cyprinus carpio). Environmental toxicology and chemistry. 2004 Aug;23(8):1939–46.
• Letcher RJ, McKinney M, Stapleton HM, Verreault J, Gabrielsen G, Scipione F, et al. Biotransformation and persistent metabolites of organohalogen contaminants in model marine and aquatic wildlife and populations. In: DRUG METABOLISM REVIEWS. TAYLOR & FRANCIS INC; 2004. p. 25–25.
• Stapleton HM, Letcher RJ, Baker JE. Debromination of polybrominated diphenyl ether congeners BDE 99 and BDE 183 in the intestinal tract of the common carp (Cyprinus carpio). Environmental science & technology. 2004 Feb;38(4):1054–61.
• Stapleton HM, Alaee M, Letcher RJ, Baker JE. Debromination of the flame retardant decabromodiphenyl ether by juvenile carp (Cyprinus carpio) following dietary exposure. Environmental science & technology. 2004 Jan;38(1):112–9.
• Hale RC, Alaee M, Manchester-Neesvig JB, Stapleton HM, Ikonomou MG. Polybrominated diphenyl ether flame retardants in the North American environment. Environment international. 2003 Sep;29(6):771–9.
• Stapleton HM, Baker JE. Comparing polybrominated diphenyl ether and polychlorinated biphenyl bioaccumulation in a food web in Grand Traverse Bay, Lake Michigan. Archives of environmental contamination and toxicology. 2003 Aug;45(2):227–34.
• Ashley JTF, Moore A, Stapleton HM, Velinsky DJ, Wilhelm MP. Sedimentary nonylphenol contamination in an urbanized, industrialized segment of the Delaware River estuary, USA. Bulletin of environmental contamination and toxicology. 2003 May;70(5):978–84.
• Stapleton HM, Skubinna J, Baker JE. Seasonal dynamics of PCB and toxaphene bioaccumulation within a Lake Michigan food web. Journal of Great Lakes Research. 2002 Jan 1;28(1):52–64.
• Stapleton HM, Letcher RJ, Baker JE. Metabolism of PCBs by the deepwater sculpin (Myoxocephalus thompsoni). Environmental science & technology. 2001 Dec;35(24):4747–52.
• Schneider AR, Stapleton HM, Cornwell J, Baker JE. Recent declines in PAH, PCB, and toxaphene levels in the northern Great Lakes as determined from high resolution sediment cores. Environmental science & technology. 2001 Oct;35(19):3809–15.
• Stapleton HM, Masterson C, Skubinna J, Ostrom P, Ostrom NE, Baker JE. Accumulation of atmospheric and sedimentary PCBs and toxaphene in a Lake Michigan food web. Environmental science & technology. 2001 Aug;35(16):3287–93.
• Stapleton H, O’Grady A. Isolation techniques fur high-resolution data-acquisition systems. EDN. 2001 Feb 1;46(3):113-+.
• Stapleton HM, Letcher RJ, Baker JE. Metabolism of highly chlorinated PCBs by a Lake Michigan fish. Environ Sci Technol. 2001;35(24):4747–52.
• Stapleton H. Measure temperature in remote locations. EDN. 2000 Oct 12;45(21):194–194.